The first customers of the MEGA (Mouse Engineering Garvan/ABR) service have taken delivery of their genetically modified founder mice.
Of the 19 mice produced from embryos microinjected with gene-specific CRISPR/Cas9 constructs, 7 founder mice were obtained – a 37% success rate and in less than 4 months from their initial expression of interest. The CRISPR/Cas9 technology can produce constitutive knockouts, single nucleotide mutations or insertions.
For further information on the MEGA Service or to book in your project visit our Genome Editing page.