Australian BioResources (ABR) believes quality mice are essential for research
The standardisation of mice, in terms of health, genetics and housing, is critical in reducing variability in research. ABR has a comprehensive quality control programme to ensure mice are of the highest standard.
To meet the high standards mice are monitored to ensure they are disease free and they have the genotypes required for research. They are housed in rooms with standardised temperature, humidity and light cycle. The housing and husbandry is optimised to promote health and well-being.
Individual records of all mice are maintained on the Stuart animal management software, facilitating the tracking of parentage and genotypes. Genetic drift in background strains is monitored using SNP panels and minimised by regularly refreshing key background strains from international repositories such as The Jackson Laboratory.
Mice at Australian BioResources are held in separate areas according to health status. Please refer to Health monitoring for further information on health status and the ABR exclusion list.
The health screening results are monitored by an in-house veterinarian.
The genotype of genetically modified mouse lines is monitored by researchers to ensure genetic quality.
The welfare of laboratory animals is regulated under the NSW Animal Research Act (1985).
The environment of the mice must be standardised to minimise experimental variability.